WHEN CORONA VIRUS WILL END.

             LIKE ALL VIRUSES EXISTING IN THIS WORLD, DOES COVID-19 WILL REMAIN EXIST FOREVER.

                                                         

                                  

 Covid-19 will NOT END in any near future, let us be very realistic. I have drawn some reasonable conclusions based on some understanding of viruses and epidemics. I will not be too technical as it hardly adds much to the appreciation of huge capability of nature.

Covid-19 is the disease caused by SARS-COVID-2 virus. This virus has shown itself to be very contagious with short incubation period in humans. The pandemic however will end, but you will continue to get sporadic outbreaks with possibly seasonal patterns. You cannot have reliable vaccines as in small pox and polio. The covid-19 is a RNA virus and likes to mutate very comfortably. The worst of its aggression will tone down after talking the toll of hundreds of thousands of elderly and twisting the world economy like never before. This may take around six months. Humans would then learn to live with this virus like a NASTY FLU BUG which  will hit them every season Those with comorbidities’ will continue to pay heavier price.

In brief, the virus lives in some exotic creatures like cockroaches, humans are similar when it comes to food habits. In the humans, it found it very easy to multiply and spread infection largely through contact, the preventive measure of social distancing, wearing masks and hand washing is related to this aspect.

The new human host now aggressively leading to morbidity and mortality. Some mutations take place and more to come across. These mutations can make it more aggressive or less. The other point is if you kill your host you cannot survive outside your prey. This is evolutionary and follows the rules of survival. The covid-virus will not end but humans will learn to live with it by sacrificing with reduced ability to fight while the majority of the rest will develop some immunity. Every season we should expect a few thousands to depart their bodies for years to come. It remains to be seen the hot weather, humidity and sunshine helps to limit its spread.

Drugs and Vaccines are long way off in terms of cure or prophylaxis; drugs are likely to help, only up to an extent, once available widely. Rapid mutations makes vaccines hard to be of great efficiency and hence to be of great use.

MRC Executive Chair, Professor Fiona Watt, said: Professor Sarah Gilbert putting their coronavirus vaccine into early-stage clinical trials in humans so quickly.

“The speed at which the UKRI-funded teams at the University of Oxford and Imperial College London have developed potential coronavirus vaccines is unprecedented.”

The ChAdOx1 nCoV-19 vaccine is made from a virus (ChAdOx1), which is a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees, that has been genetically changed so that it is impossible for it to grow in humans.

Genetic material has been added to the ChAdOx1 construct, that is used to make proteins from the COVID-19 virus (SARS-CoV-2) called Spike glycoprotein (S). This protein is usually found on the surface of SARS-CoV-2 and plays an essential role in the infection pathway of the SARS-CoV-2 virus. The SARS-CoV-2 coronavirus uses its spike protein to bind to ACE2 receptors on human cells to gain entry to the cells and cause an infection.

By vaccinating with ChAdOx1 nCoV-19, they are hoping to make the body recognise and develop an immune response to the Spike protein that will help stop the SARS-CoV-2 virus from entering human cells and therefore prevent infection.

Vaccines made from the ChAdOx1 virus have been given to more than 320 people to date and have been shown to be safe and well tolerated, although they can cause temporary side effects, such as a temperature, headache or sore arm.

This story is based on content provided by the University of Oxford – read more on their site or find out more on the vaccine trial page.